Make the most of your resources, by converting
your RNA-seq data into better proteomics coverage!
In most proteomics experiments, identifications rely on the Database Searching strategy, which means you only identify what you expect to see. The search database is typically the species’ standard proteome. This means that any individual-specific peptide polymorphisms cannot normally be detected. This issue is particularly valid for personalised medicine, where these polymorphisms may be the reason behind differences in the responses of patients to treatments.
However, it is increasingly the case that people perform both transcriptome and proteome analysis in parallel. It is possible to use mRNA transcript-level information to estimate individual-specific proteomes. By offering this new service, DC Biosciences steps resolutely into the world of next-generation, integrative proteomics.